Admitted AIDS-associated Kaposi sarcoma patients
نویسندگان
چکیده
منابع مشابه
Kaposi Sarcoma-Associated Herpesvirus
Kaposi sarcoma-associated herpesvirus (KSHV) is known to be a human carcinogen based on sufficient evidence from studies in humans. This conclusion is based on evidence from epidemiological and molecular studies, which show that KSHV causes Kaposi sarcoma, primary effusion lymphoma, and a plasmablastic variant of multicentric Castleman disease, and on supporting mechanistic data. KSHV causes ca...
متن کاملAIDS-Kaposi Sarcoma and Classic Kaposi Sarcoma: are different ultrasound patterns related to different variants?
BACKGROUND Kaposi Sarcoma (KS) is a malignancy of endothelial skin cells with multifocal localization on the skin, lymph nodes and visceral organs. Although all clinical variants are associated with HHV-8 infection, specific differences in the clinical onset and in the natural history of AIDS-KS and Classic-KS have been described. The present randomised prospective-observational study aimed to ...
متن کامل[Kaposi sarcoma associated with infliximab treatment].
Tumor necrosis factor a antagonists alter the inflammatory response, which leads to an increased risk of infections1,2 and neoplasms. Such neoplasms include Kaposi sarcoma, a tumor of the vascular endothelium described by Moritz Kaposi in 1872. We describe the case of a patient who developed Kaposi sarcoma following infliximab therapy for corticosteroiddependent ileal Crohn disease. The patient...
متن کامل[Kaposi sarcoma associated with systemic corticosteroid therapy].
Kaposi sarcoma (KS) was first described in 1872 by Moritz Kaposi. Its epidemiology is suggestive of an infectious disease and in 1994 Chang and coworkers identified DNA sequences corresponding to a previously unidentified herpes virus--human herpes virus 8 (HHV-8)--in AIDS-associated KS biopsies. It is now believed that the presence of HHV-8 is a necessary condition but not sufficient on its ow...
متن کاملActivity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma.
Interleukin-12 (IL-12) enhances Th1-type T-cell responses and exerts antiangiogenic effects. We initiated a phase 1 pilot study of IL-12 in 32 patients with acquired immunodeficiency syndrome (AIDS)-related Kaposi sarcoma (KS) whose KS was progressing while on antiretroviral therapy. Fifteen patients had poor prognosis T(1)S(1) disease. IL-12 was administered subcutaneously twice weekly at dose...
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ژورنال
عنوان ژورنال: Medicine
سال: 2020
ISSN: 0025-7974,1536-5964
DOI: 10.1097/md.0000000000022415